The "Spanish flu" virus of 1918 killed an estimated 50 million people, more than all the deaths in World War I combined. While global public health efforts have greatly improved mortality rates in more modern outbreaks, experts say the next pandemic is a matter of "when," not "if." In this episode, Ian Bremmer takes a look how diseases spread and become global. His guest, Dr. Anthony Fauci, is a leading epidemiologist and director of the National Institute of Allergy and Infectious Diseases at the NIH.

Dr. Fauci breaks down some of the biggest health threats facing the world today: HIV/AIDS, Ebola, malaria, tuberculosis, influenza, and the recent rise in cases of measles brought on by the misguided anti-vaccine movement.

Also on the show: Five years after his Ebola diagnosis made international news, NYC's Dr. Craig Spencer tells GZERO Media what he learned from the experience and what his life is like today.

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Three months into the Iran war, the Strait of Hormuz is in a standoff and the geopolitical fallout is spreading fast. Kori Schake of the American Enterprise Institute breaks down with Ian Bremmer what the conflict means for US power and the ambitions of Russia and China.

US President Donald Trump participates in an arrival ceremony at Beijing Capital International Airport during his visit to the country, in Beijing, China, on May 13, 2026.
REUTERS/Evan Vucci

Xi Jinping will welcome Donald Trump with lots of pomp and circumstance. The summit, though, will be short on substance.