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Almost everyone in Iran “just waiting for Ayatollah Khamenei to die”

Who comes next in Iran’s leadership succession? Karim Sadjadpour says “almost everyone” inside both Iranian society and the regime is waiting for 86-year-old Ayatollah Khamenei to die. Even elements of the Revolutionary Guards know “this status quo is not tenable,” but fear of surveillance and repression makes any internal coup too risky —for now.

That raises a bigger question: does Khamenei’s looming succession make external military action more tempting or more dangerous? Sadjadpour calls it a “51-49” decision. “Military attack is a gamble,” he warns.

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The US and Israel struck Iran. What happens next?

The US and Israel struck several sites in coordinated attacks across Iran this morning. The total number of casualties across Iran is also unknown, though one of the missiles hit a girls’ school in Iran, reportedly killing 53 people. The country is under a near-total internet blackout.

In response, Tehran has launched airstrikes at Israel, as well as US bases throughout the region, including in Bahrain, Kuwait, Qatar, and the United Arab Emirates. Though many of the strikes have been intercepted, shrapnel has caused some damage. One Iranian missile that was likely intended to hit Israel landed instead in Syria, killing four.

Ian Bremmer gives his analysis of the situation, which he calls a “war of regime change.” The United States is “a uniquely powerful global actor militarily, and now has a president who feels pretty unconstrained in using that military directly for political outcomes of his choosing,” Ian explains. “That clearly can cause a lot of disruption.”

What happens next? The fighting could escalate into a larger conflict. The US and Israel are reportedly planning several days of intensive strikes, with the Israeli Defense Forces calling up 70,000 reservists. There are also questions now as to whether Iran’s retaliatory strikes on US bases in several Middle East states prompt more countries to get involved.

But the most pressing question at this time is about Supreme Leader Ali Khamenei. As of the moment of this publication, his whereabouts and condition are unknown following the strike on his compound. Iran’s foreign minister said Khamenei is alive “as far as I know,” but there are reports that several senior regime leaders have been killed. In a video posted on social media on Saturday, US President Donald Trump urged Iranian citizens to topple the regime.

“When we are finished, take over your government,” Trump said. “This will be, probably, your only chance for generations.”

The United Nations Security Council is set to hold an emergency session at 4 pm ET today, after requests from Iran, Bahrain, France, and other countries. Iran’s foreign minister argued that the United States had violated international law in attacking Iran.

What happens if Khamenei is killed? The death of the 86-year-old would be a huge shock to the country’s political system, Eurasia Group’s Iran expert Greg Brew told us earlier this month. However, it wouldn’t necessarily lead to a long-term shift in the regime.

“Overall, however, it may not change much – at least not at first,” said Brew. “The rest of the leadership would manage a transition to a new supreme leader, and much of the Islamic Republic would probably continue to function as it has done for years. In the medium-term, however, Khamenei’s disappearance would trigger changes within the system, as the military and Islamic Revolutionary Guard Corps assume more power over decision-making while the clerics – including Khamenei’s replacement – take a back seat.”

Reza Pahlavi, the exiled son of the former Iranian shah, has been saying for months that the Iranian people want him to return to the country and lead it. Whether this is a realistic option is unclear.

Back up: Why is Trump doing this? In his video, Trump described Iran, as well as its Middle East proxies, as a major threat to the United States, saying they are the “number one state sponsor of terror.” He reiterated that he cannot let the Islamic Republic have a nuclear weapon. The US leader added that he was heeding calls from the Iranian people who wanted to see Khamenei’s regime fall.

Trump, who had been threatening strikes against Iran since and rapidly expanding the US military presence in the region, may also be seizing an opportune moment to destroy one of the US’s greatest foes. The Islamic Republic is weaker than ever: its economy has been decimated by sanctions and mismanagement, its air defenses have been depleted from last summer’s 12-day war with Israel and the US, its own people have been in open revolt against the regime, and its regional proxies – such as Hamas and Hezbollah – are battered and bruised.

One concern for Trump is whether these strikes will repel the isolationist portion of the MAGA coalition. The US president acknowledged that “the lives of courageous American heroes may be lost,” but tried to mollify any potential opposition by saying, “We’re doing this not for now, we’re doing this for the future.” Nonetheless, opposition is already emerging: Sen. Rand Paul, a Republican from Kentucky, criticized this morning’s strikes, saying Trump didn’t have the approval from Congress needed to initiate a war.

What’s the reaction been in the Middle East? Several US allies in the Gulf, including Saudi Arabia, Qatar, and Oman, had been urging Washington not to strike Iran, fearful that it would spark a regional war. Tehran’s reserves of close-range ballistic missiles, which cannot reach Israel but can get to the US bases in the Gulf, add another layer of concern for countries in the region.

After the Islamic Republic fired at some of those bases today, there are questions over whether those countries will now get involved in this conflict. Thus far, the focus of these Gulf states has been on shooting down missiles fired in their direction, rather than in any offensive moves.

The US and Israel launch war on Iran

The United States and Israel have launched massive military strikes on Iran. The stated goal: dismantle Iran’s nuclear program and ballistic missile capabilities. The unstated but increasingly clear objective: regime change.

In this Quick Take, Ian Bremmer breaks down what this means.

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Iran at war with Carnegie’s Karim Sadjadpour


Listen: Ian Bremmer sits down with Karim Sadjadpour of the Carnegie Endowment for Peace to examine Iran’s precarious position on the global stage and the forces shaping the country. At the heart of the discussion is the regime’s internal fragility. Sadjadpour explains that many inside Iran, including elements of the Revolutionary Guards, are “waiting for Ayatollah Khamenei to die.”

The conversation also explores Iran’s isolation in the international arena. While 90% of its oil goes to China at deep discounts, Sadjadpour points out that Chinese and Russian interests in Iran diverge sharply. Despite the pressures at home and abroad, Sadjadpour argues that many ordinary Iranians recognize that reconciliation with the United States is essential if the country is ever to realize its enormous potential.

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Is the US on the brink of war with Iran?

NOTE: This episode was recorded before the US and Israel launched strikes into Iran. While events have moved quickly since then, the geopolitical state of play and key thinking leading up to this attack remains relevant.

Despite ongoing negotiations, President Trump is signaling that military pressure may be the only way to force Tehran’s hand. This week, Ian Bremmer speaks with Karim Sadjadpour, Senior Fellow at the Carnegie Endowment for Peace, who argues the president’s past Iran gambles have “been vindicated”, making further action more likely.

If strikes come, Iran has hinted that they’re going to regionalize the war, potentially targeting US bases or Gulf oil infrastructure. Inside Iran, meanwhile, there is “no country in the world with a greater gap between the aspirations of its people and the conduct of its government.” Whether escalation weakens the regime or strengthens it, Sadjadpour cautions, “military attack is a gamble”—and “no one can predict what comes after that.”

$4 billion: The amount Kenya wants to raise in order to complete a partially built railway line that was abandoned in 2019. The project, which will link Nairobi with South Sudan, Uganda, and Kenya, came to a halt after initial funding from China dried up. This time around, Kenya wants to finance the project itself, through new import tariffs, rather than return to Beijing. It would be the country’s biggest infrastructure project since gaining independence from Britain in 1963.
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Trump pushes Zelensky for ASAP peace deal

In a 30-minute call on Thursday, President Donald Trump reportedly told Ukrainian President Volodymyr Zelensky he wants to end the war with Russia as soon as possible — aiming for a deal by summer, but ideally within weeks. Trump reiterated his willingness to provide Ukraine with significant US security guarantees as negotiations continue. But Zelensky faces a delicate challenge of adapting to Trump’s transactional approach to peacemaking. Trump’s urgency is partly driven by a desire to reopen US-Russia commerce, which could help revive Russia’s economy and ultimately weaken the credibility of US security commitments to Ukraine. As former NATO ambassador Ivo Daalder warned during a recent GZERO World interview, a ceasefire could become a “trap” if it means the US opens up economic relationships with Russia — like weakened sanctions and pushing Europeans to release $300 billion in Russian frozen assets. As a result, post-war security commitments to Ukraine could lose their credibility.

US strikes billion dollar health partnership with Congo

Washington agreed on Thursday to provide $900 million to help the mineral-rich African nation combat HIV/AIDS, advance maternal and child health, and fight infectious diseases. In return, Congo will put up $300 million of its own money. The pact comes just weeks after the US and Kinshasa inked a controversial deal giving US companies access to Congo’s critical minerals. The Trump administration has struck more than a dozen bilateral health agreements with African nations since eliminating USAID, the US’s main foreign aid agency. Supporters of the “trade-not-aid”-style deals say they reduce recipient countries’ aid dependency and provide more tangible benefits for the US. Critics say they are opaque, and have raised concerns about provisions that may give US companies access to Africans’ personal health data.

The ghost of Jeffrey Epstein continues to haunt the world.

This week kicked off with British police arresting Peter Mandelson, former UK ambassador to Washington, on suspicion of “misconduct in public office” from his time as business secretary between 2008 and 2010. Mandelson wasn’t named in the arrest records, part of the UK’s rules banning them from identifying suspects before charges are brought. But Epstein’s emails, released by the US Justice Department, suggest Mandelson may have shared an internal government report with the ex-financier.

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Think you know what's going on around the world? Here's your chance to prove it.

President Trump spoke for 108 minutes during his State of the Union address, making it the longest speech for a president before Congress. Who held the record before?

  • A) Joe Biden
  • B) Bill Clinton
  • C) Donald Trump

Take the quiz to see if you guessed correctly!

Modi, Netanyahu seek to boost India-Israel ties

India is set to advance a trade and defense technology deal with Israel, Prime Minister Narendra Modi said as he wrapped up a two-day visit to the Jewish state on Thursday, the latest sign that the relationship is blossoming. But the two countries weren’t always close friends – they only established full diplomatic relations in 1992 – but Modi has long been an ally of Israeli Prime Minister Benjamin Netanyahu, and became the first Indian PM to visit Israel back in 2017. Today, India is Israel’s largest arms buyer, accounting for 34% of the country’s weapon exports. Modi’s second-ever trip to Israel this week also marks another step toward reshaping alliances in the Middle East and beyond, as India’s rival Pakistan boosts defense links with Saudi Arabia, while the UAE shifts away from Riyadh and toward Israel and India.

Colombia’s Petro hits new highs late in the game

With just three months left in office, Colombian President Gustavo Petro is hitting some of his highest approval ratings, nearing 50% in a new poll. That’s a staggering 11 point jump since December, when the left-winger was on the ropes over a stagnating economy, a worsening security crisis, and tensions with the US over Gaza, Venezuela, and the “war on drugs.” But Petro’s deft combination of firm pushback against Donald Trump and pragmatic engagement with the US president – the two met at the White House earlier this month – yielded political dividends, not only for him, but for his preferred successor, far-left Senator Iván Cepeda, who leads the polls ahead of the May election. That race is shaping up to be a stark choice between Cepeda and right-wing lawyer Abelardo de La Espriella.

Pentagon and Anthropic go toe-to-toe over AI use

Defense Secretary Pete Hegseth has given the AI company Anthropic until 5:01 pm tomorrow to agree to allow the US military unrestricted use of its technology, known as Claude. Right now, Claude is the only AI running in the military’s classified systems, but the company wants reassurances that it’s not being used for surveillance of Americans or to conduct military strikes without human oversight. However, the Pentagon doesn’t want to have to ask Anthropic about individual use cases. Hegseth has threatened to use the Defense Production Act, which would force the company to give it access to Claude and simultaneously label the company a supply chain risk. The discussions come the same week that Anthropic scaled back its safety pledge, raising the stakes in a showdown between national security demands, personal privacy, and AI guardrails.
History doesn’t often repeat itself, but it does rhyme. Such appears to be the case, as the United States appears again to be readying for military action against Iran. Just as last summer when US and Iranian officials held five rounds of nuclear talks only to find a deal evasive, this month has brought a series of indirect negotiations between the sides bearing little progress.
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