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The United States will no longer play global policeman, and no one else wants the job. This is not a G-7 or a G-20 world. Welcome to the GZERO, a world made volatile by an intensifying international battle for power and influence. Every week on this podcast, Ian Bremmer will interview the world leaders and the thought leaders shaping our GZERO World.

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How AI will revolutionize medicine, and cancer research

How AI will revolutionize medicine with Siddhartha Mukherjee

Ian Bremmer sits down with physician and author Siddhartha Mukherjee to explore how AI is revolutionizing cancer treatment and drug discovery.

Listen: Nearly 1 in 2 men and 1 in 3 women in the US will be diagnosed with cancer, and 1,700 people die from it every day. Disparities persist—Black women are 40% more likely to die of breast cancer than white women—and treatment costs remain crushing for many.

On the latest episode of the GZERO World podcast, Ian Bremmer talks with world-renowned cancer researcher and Pulitzer Prize-winning author Siddhartha Mukherjee about the future of medicine—and why artificial intelligence might finally tip the scales in the decades-long war on cancer.


Cancer remains the second leading cause of death in the US, killing nearly 1,700 people every day. But Mukherjee says AI is already reshaping the field, from radiology and diagnostics to identifying new carcinogens and designing entirely new cancer drugs. “Every time we do this in collaboration with a machine,” he explains, “the machine learns it, and it learns it forever.”
In a wide-ranging conversation, Mukherjee breaks down three major areas where AI is advancing medicine: patient care, data mining, and generative drug development. He also weighs in on early cancer detection, how inflammation may hold the key to understanding new carcinogens, and why this moment may be the most hopeful in half a century of cancer research.

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Bioweapons, AI, and the end of the world, with Annie Jacobsen

For decades, nuclear war has represented the ultimate doomsday scenario. But investigative journalist and author Annie Jacobsen says biological warfare may pose an even greater overall threat. Unlike nuclear weapons, which require tightly controlled materials, enormously expensive delivery systems, and specialized expertise, the barriers to developing biological weapons can be far lower. And artificial intelligence could lower them further.

Ian Bremmer sits down with Jacobsen to discuss how AI is changing the landscape of catastrophic risk. As increasingly powerful models make sophisticated scientific knowledge easier to access, they could allow bad actors to bypass years of specialized training and dramatically shorten the path from an idea to a potentially dangerous capability.

They also explore the struggle to govern a technology developing faster than regulators can respond, the gaps in existing AI safeguards, and what governments and tech companies could do to identify dangerous vulnerabilities before they are exploited. And they step back to a larger question at the heart of Jacobsen’s work: Why does humanity keep developing technologies with the potential to threaten its own survival – and can our ability to manage those risks ever catch up with our ability to create them?

AI is rapidly lowering the barriers to knowledge and expertise that once kept some of humanity’s most dangerous capabilities out of reach. Investigative journalist Annie Jacobsen joins Ian Bremmer to... More >

The enduring legacy of 9/11, with former Defense Secretary Mark Esper


This week marks 25 years since 9/11—the deadliest terror attack the world has ever seen and a defining moment in American history. The attacks transformed US politics and national security. The war on terror became the organizing principle of American foreign policy. Former Secretary of Defense Mark Esper joins Ian Bremmer on the GZERO World Podcast to reflect on the day that forever changed how Americans thought about national security, and how the United States wielded its enormous power around the world.
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Former Defense Secretary Mark Esper reflects on 25 years since 9/11, the lessons of America’s forever wars, and the biggest threats to US national security today... More >

The race to build humanity's future in space, with Chris Hadfield

More than half a century after humans last walked on the Moon, the next era of space exploration is taking shape. Getting there is cheaper, private companies are playing a much bigger role, and discoveries like vast reserves of lunar water have made the prospect of establishing a permanent presence on the Moon far more realistic.

Ian Bremmer sits down with Canadian astronaut Chris Hadfield to talk about what this new space age could look like. They discuss the growing competition between the US and China, whether rivals can cooperate on the lunar surface, and who gets to write the rules as governments and companies begin looking beyond simply planting a flag.

Hadfield also breaks down the practical challenges of living on the Moon – from powering a settlement through long lunar nights to the unanswered question of whether humans can develop normally in low gravity. He explains how private companies are turning space into a commercial marketplace, why regulation will inevitably struggle to keep pace, and why robots alone can never satisfy humanity’s drive to explore Mars.

And drawing on nearly six months aboard the International Space Station, Hadfield reflects on the surprisingly wonderful experience of sleeping in zero gravity, circling Earth 2,600 times, and how seeing the planet from above fundamentally changed his perspective on humanity and our place in the universe.

The race to the Moon is back – but reaching it is only the beginning. Astronaut Chris Hadfield joins Ian Bremmer to explore how cheaper technology, private industry, and growing US-China competition... More >

The global aid crisis, with David Miliband

What happens when the world’s safety net disappears? For decades, international aid has helped fight poverty, stop disease outbreaks, and keep fragile societies from falling over the edge. But after the shutdown of USAID last year, the relief system is in danger of collapsing entirely. International Rescue Committee President & CEO David Miliband joins Ian Bremmer on the GZERO World Podcast to talk about the long shadow cast by America’s retreat from global aid and what comes next.

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Humanitarian aid isn’t just charity—it’s the world’s safety net against disease, conflict, and instability. David Miliband joins Ian Bremmer to unpack what America’s retreat from global aid means for... More >

GZERO Podcasts

AI is rapidly lowering the barriers to knowledge and expertise that once kept some of humanity’s most dangerous capabilities out of reach. Investigative journalist Annie Jacobsen joins Ian Bremmer to... More >

Listen: What does global energy transition look like in a time of major geopolitical change, including rebalancing of trade? In this special episode of "Energized: The Future of Energy,” host JJ... More >

Creating artificial human retinas in zero gravity. Mining rare minerals on the moon. There seems to be no limit to what could be possible if we continue to take our more important industries to... More >

On the sidelines of the 81st United Nations General Assembly, GZERO Media’s Tony Maciulis sits down with Fred Werner of the International Telecommunication Union (ITU) to discuss the opportunities... More >

In this episode of The Ripple Effect: Investing in Life Sciences, host Dan Riskin speaks with Patrick Horber, President of Novartis International, and David Gluckman, Vice Chairman of Investment... More >