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How AI will revolutionize medicine with Siddhartha Mukherjee
Listen: Nearly 1 in 2 men and 1 in 3 women in the US will be diagnosed with cancer, and 1,700 people die from it every day. Disparities persist—Black women are 40% more likely to die of breast cancer than white women—and treatment costs remain crushing for many.
On the latest episode of the GZERO World podcast, Ian Bremmer talks with world-renowned cancer researcher and Pulitzer Prize-winning author Siddhartha Mukherjee about the future of medicine—and why artificial intelligence might finally tip the scales in the decades-long war on cancer.
Cancer remains the second leading cause of death in the US, killing nearly 1,700 people every day. But Mukherjee says AI is already reshaping the field, from radiology and diagnostics to identifying new carcinogens and designing entirely new cancer drugs. “Every time we do this in collaboration with a machine,” he explains, “the machine learns it, and it learns it forever.”
In a wide-ranging conversation, Mukherjee breaks down three major areas where AI is advancing medicine: patient care, data mining, and generative drug development. He also weighs in on early cancer detection, how inflammation may hold the key to understanding new carcinogens, and why this moment may be the most hopeful in half a century of cancer research.
Subscribe to the GZERO World Podcast on Apple Podcasts, Spotify, Stitcher, or your preferred podcast platform, to receive new episodes as soon as they're published
The new global trade wars, with Fareed Zakaria
President Trump’s policies swiftly rewriting the rules of global trade. As the United States imposes tariffs on allies and adversaries alike, do we risk losing our edge? On the GZERO World Podcast, CNN’s Fareed Zakaria joins Ian Bremmer to discuss what happens when globalization’s biggest champion becomes its biggest critic. For the past 80 years, the United States has been the beating heart of the free trade movement, the country that forced all the other countries in the world to open their markets. But now, Washington is tearing up the economic playbook—levying historic tariffs and recasting the world as a high-stakes, winner-take-all, zero-sum game.
Zakaria says we are living through an age of backlash to 30 years of globalization and that the next 10 years will be a period of “slowbalization,” where we'll see a much slower pace of growth and a much more political economy. Bremmer and Zakaria break down America’s retreat from global leadership, shifting power dynamics between the US and China, European pressure to become more self-sufficient, and whether the Trump administration’s economic gamble is worth the risk.
“The United States has gone from the leading advocate of free trade to being the most protectionist advanced industrial country in the world,” Zakaria warns, “We’ve always invited competition from the world’s best. If we move to something else, I think we lose that edge.”
Could the future of industry lie among the stars?
Listen: Creating artificial human retinas in zero gravity. Mining rare minerals on the moon. There seems to be no limit to what could be possible if we continue to take our more important industries to space. Join Mike Massimino and Mike Greenley on this episode of Next Giant Leap as they explore the industrialization of space. Dr. Joan Saary sheds light on the potential of designing medical treatments in microgravity and treating astronauts in orbit, and Dr. Gordon Osinski explains the exciting future of resource extraction on other planetary objects.
Next Giant Leap, hosted by MDA Space CEO Mike Greenley and former NASA astronaut Mike Massimino, is a podcast series that explores how business and innovation are transforming space—and life on Earth. From national security to military technology to medical discoveries, the two Mikes talk to leading experts about the risks, opportunities, and big questions of the new Space Age.
The two trillion dollar opportunity
Listen: You might not know it, but you interact with space technology countless times on a daily basis. In fact, the space economy has become so ubiquitous that some estimate that its value could reach as high as $1.8 trillion by 2035. On this episode of Next Giant Leap, hosts Mike Massimino and Mike Greenley are joined by Alex MacDonald, former Chief Economist at NASA. They discuss the surprising history of private investment in the space industry, the many reasons for the current boom, and how you might get a job in the space world.
Next Giant Leap, hosted by MDA Space CEO Mike Greenley and former NASA astronaut Mike Massimino, is a podcast series that explores how business and innovation are transforming space—and life on Earth. From national security to military technology to medical discoveries, the two Mikes talk to leading experts about the risks, opportunities, and big questions of the new Space Age.
A new era of space defense
Listen: For many of us, the idea of a space-based arm of the military calls to mind images from science fiction. But the real-life world of space defense has become increasingly integral to military operations on land, at sea, and in the air. In this episode of Next Giant Leap, hosts Mike Massimino and Mike Greenley explore the world of space military technology. Guests Major General (Ret.) Kim Crider formerly of the United States Space Force, and Brigadier-General Chris Horner of the Canadian Space Division walk us through the many innovations in this fascinating arena, and attempt to answer one crucial question: how do you secure a domain with no borders?
Next Giant Leap, hosted by MDA Space CEO Mike Greenley and former NASA astronaut Mike Massimino, is a podcast series that explores how business and innovation are transforming space—and life on Earth. From national security to military technology to medical discoveries, the two Mikes talk to leading experts about the risks, opportunities, and big questions of the new Space Age.
What's next for Iran, with Thomas L. Friedman
Listen: On the latest episode of the GZERO World podcast, Ian Bremmer sits down with New York Times columnist Thomas L. Friedman to dissect what may go down as the most consequential month in the Middle East in years. Just weeks after Israel launched a war against Iran—and after President Trump authorized US airstrikes—an uneasy ceasefire is in place. But what was actually achieved?
Iran, the clear loser of the 12-Day War, entered as the most vulnerable player and emerged weaker still. Tehran stood largely alone, with Hamas degraded, Hezbollah decimated, Syria toppled, and Russia distracted. Yet the Islamic Republic can still claim regime survival, some damage inflicted on Israel, and a murkily intact nuclear program.
Netanyahu, meanwhile, avoided a ceasefire until he had secured key gains: he crippled Iran’s infrastructure, leveraged US firepower to hit targets beyond Israel’s reach, and rescued his collapsing political career. As Friedman notes, “The people who won this war for Israel...were, for the most part, the very same people who were in the streets of Israel for nine months against Netanyahu and his judicial coup.” That tension will only grow in the months ahead.
Subscribe to the GZERO World Podcast on Apple Podcasts, Spotify, Stitcher, or your preferred podcast platform, to receive new episodes as soon as they're publishedWhy life sciences are critical to national security
Listen: What if the next virus isn’t natural, but deliberately engineered and used as a weapon? As geopolitical tensions rise and biological threats become more complex, health security and life sciences are emerging as critical pillars of national defense.
In the premiere episode of “The Ripple Effect: Investing in Life Sciences”, host Dan Riskin is joined by two leading voices at the intersection of biotechnology and defense, Dawn Meyerriecks, former CIA Deputy Director for Science and Technology and current member of the National Security Commission on Emerging Biotechnology, and Jason Kelly, co-founder and CEO of Ginkgo Bioworks. Together, they explore the dual-use nature of biotechnology and the urgent need for international oversight, genetic attribution standards, and robust viral surveillance. From pandemic preparedness and fragile supply chains to AI-driven lab automation and airport biosurveillance, their conversation highlights how life science innovation strengthens national resilience and strategic defense.
This timely conversation follows the June 25th, 2025 Hague Summit Declaration, where NATO allies pledged to invest 5% of GDP in defense by 2035—including up to 1.5% on resilience and innovation to safeguard critical infrastructure, civil preparedness, networks, and the defense industrial base. This limited series, produced by GZERO’s Blue Circle Studios in partnership with Novartis, examines how life science innovation plays a vital role in fulfilling that commitment.
Where middle class growth and small business meet
Listen: Small businesses are more than just corner shops and local services. They’re a driving force of economic growth, making up 90% of all businesses globally. As the global middle class rapidly expands, new opportunities are emerging for entrepreneurs to launch and grow small businesses.
In the first episode of “Local to global: The power of small business”, host JJ Ramberg sits down with Shamina Singh, Founder and President of the Mastercard Center for Inclusive Growth, and Homi Kharas, Senior Fellow at Brookings Institution and Co-Founder of the World Data Lab. Together, they explore how the spending power of the global middle class is fueling small business growth from Taipei to Toronto and beyond.
The discussion also highlights how digital inclusion, access to finance, and cybersecurity are essential for small business success.
“Local to global: The power of small business” is a new podcast series from GZERO Media's Blue Circle Studios and Mastercard, where we'll look behind the curtain to explore the world of small businesses and why they’re positioned to play an even bigger role in the future of the global economy.