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What are the “known unknowns” about Moderna’s vaccine?

Moderna co-founder Noubar Afeyan concedes that there is plenty he still doesn't know about his company's COVID-19 vaccine, just as there's plenty he still doesn't know about the virus. But he is confident about one thing: "I view the vaccine as the best mask. It's a molecular mask, and once we have it onboard once, then presumably it will protect us." His conversation with Ian Bremmer was part of the latest episode of GZERO World.

Watch the GZERO World episode: A Shot in the Arm: Moderna's Co-Founder on the COVID-19 Vaccine

Khant Thaw Htoo is a young engineer who works in Eni's Sakura Tower office in the heart of Yangon. As an HSE engineer, he monitors the safety and environmental impact of onshore and offshore operations. He also looks out for his parents' well-being, in keeping with Myanmar's traditions.

Learn more about Khant in the final episode of the Faces of Eni series, which focuses on Eni's employees around the world.

On his first day as president, Joe Biden signed a remarkable series of executive orders. Boom! The US rejoins the Paris Climate Accord. Bang! The United States rejoins the World Health Organization. Pow! No more ban on immigration from many Muslim-majority countries. Biden's press secretary reminded reporters later in the day that all these orders merely begin complex processes that take time, but the impact is still dramatic.

If you lead a country allied with the US, or you're simply hoping for some specific commitment or clear and credible statement of purpose from the US government, you might feel a little dizzy today. The sight of an American president (Barack Obama) signing his name, of the next president (Donald Trump) erasing that name from the same legislation/bill, and then the following president (Biden) signing it back into law again will raise deep concerns over the long-term reliability of the world's still-most-powerful nation.

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Now that Joe Biden is officially US president, leaders from around the world would like a word with him — but where will he make his first international trip?

After a tumultuous four years, many countries are now clamoring for a face-to-face with President Biden. That includes allies who felt abandoned by Trump's "America First" presidency, as well as adversaries with thorny issues on the agenda. We check in on who's pitching him hardest on a near-term state visit.

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Brexit pettiness lingers: Here we were naively thinking the Brexit shenanigans were over after the EU and UK agreed to an eleventh-hour post-Brexit trade deal last month. We were wrong — the saga continues. Now, a new row has erupted after the Johnson government said it will not give the EU ambassador in London the same diplomatic status awarded to other representatives of nation states. Unsurprisingly, this announcement peeved Brussels, whose delegates enjoy full diplomatic status in at least 142 other countries. The UK says it will give the EU envoy the same privileges as those given to international organizations, which are subject to change and do not include immunity from detention and taxation given to diplomats under the Vienna Convention on diplomatic relations. EU members are furious, with officials accusing London of simply trying to flex its muscles and engaging in "petty" behavior. The two sides will discuss the matter further when European Commission chief Ursula von der Leyen and UK Prime Minister Boris Johnson meet next week, their first face-to-face since the two sides settled the Brexit quagmire on December 31. Alas, the Brexit nightmare continues.

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John Nance Garner gave up the powerful position of Speaker of the House to serve two terms as Franklin Roosevelt's vice president (1933-1941), but he's best remembered today for a comment (he may never actually have made) that the job of VP "is not worth a bucket of warm spit."

In reality, the role of US vice president is determined almost entirely by the president. With that in mind, how might Kamala Harris serve Joe Biden? A few thoughts.

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The GZERO World Podcast with Ian Bremmer. Listen now.

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